Filippo, B., Granchi, D., Roatti, G., Merlini, L., Sabattini, T., & Baldini, N. (2017). Alpha-lipoic acid after median nerve decompression at the carpal tunnel: A randomized controlled trial. The Journal of Hand Surgery, 4, 236–42.
The Skinny – A double-blind, randomized controlled study was performed. Sixty-four patients were randomly assigned into two groups after median nerve decompression. Thirty-two patients took the alpha-lipoic acid (ALA), while the other 32 received the placebo pill.
In The Weeds – The outcome measures utilized were Boston Carpal Tunnel score, 2-point discrimination, presence or absence of pillar pain, use of analgesics beyond post-op day 2, and sensory and motor conduction velocities. These measures were assessed at three months post-op.
Bringing it Home – ALA did not significantly improve nerve conduction velocity or Boston Carpal Tunnel score. Taking ALA did reduce pillar pain, and static 2-point discrimination improved in both groups.
Taking ALA for 40 days after carpal tunnel surgery can lower the incidence of Pillar Pain. The study size was relatively small, and the outcome measures of pain and two-point discrimination test are somewhat subjective measures. The ALA treatment (pillar pain treatment) was well tolerated by the study participants. A larger study is needed to confirm these findings.
More To Read
Conservative Management of Carpal Tunnel Symptoms: A Comparison of the effectiveness of orthosis wear, kinesiotaping and paraffin treatment.
Kaplan, B. M., Akyuz, G., Kokar, S., & Yagci, I. (2018). Comparison of the effectiveness of orthotic intervention, kinesiotaping, and paraffin treatments in patients with carpal tunnel syndrome: A single-blind and randomized controlled study. Journal of Hand Therapy, 32, 297-304. The Skinny The authors completed a randomized control trial with three groups to test the…Read More
Hamzeh, H., Mohammad, M., Alghwiri, A., & Hawamdeh, Z. (2021). The long-term effect of neurodynamics vs. exercise therapy on pain and function in people with carpal tunnel syndrome: A randomized parallel-group clinical trial. Journal of Hand Therapy, 34, 521-530. The Skinny: Carpal tunnel is the most common peripheral nerve compression problem. There is now some…Read More
Mirror therapy has many implications for therapy and can be used to treat many diagnoses that commonly involve the upper extremity. These include some of the Neuro Conditions we highlighted last week including, Stroke and Focal Hand Dystonia. Btw, you can download a mirror therapy exercises pdf here for free. How long should the patient…Read More
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